In a mixing bowl, combine cooked ground beef, sliced beef pepperoni, shredded mozzarella cheese, pizza sauce, and Italian seasoning. Stir until well mixed.

Place a large skillet over medium heat and add a tablespoon of olive oil. Allow the oil to heat until shimmering, about 1 to 2 minutes.

Lay one tortilla flat in the skillet, and spread half of the beef and pepperoni filling evenly across its surface. Place a second tortilla on top and gently press down.

Cook the quesadilla for 3 to 4 minutes, or until the bottom is golden brown and crispy. Flip the quesadilla and cook for another 3 to 4 minutes until equally golden and cheese is melted.

Transfer the quesadilla to a cutting board and let it cool slightly. Use a sharp knife to slice it into wedges.